The scientists used positron emission tomography, or PET, to measure brain metabolism of mice deficient in the dopamine transporter, and their normal siblings. In this technique, the researchers administered glucose (the chief brain fuel) radioactively labeled and used the PET scanner to track its concentration in different brain regions. Mice were examined before and after cocaine administration, and compared the results with those obtained in mice treated with saline instead of drugs.

After cocaine administration, cerebral metabolism was reduced in both groups of mice, but more significantly in normal.

The reduction was observed in many brain regions, probably because cocaine blocks the dopamine transporters. However, we also observed a reduction in metabolism in the thalamus region of the transporter-deficient mice. This effect is possibly due to the effect of cocaine on other neurotransmitter systems, such as serotonin or the norepinephrine.

In summary, the disorders on brain activity caused by cocaine are due, largely, to its action on dopamine, but also, to a lesser extent, its effect on norepinephrine or serotonin.

This finding will allow deeper into the understanding of the mechanism of cocaine addiction.

Cocaine is a drug that makes you confident, talkative, alert, good draw for those who find it difficult, in this way is usually the feeling. However, because the drug decreases, rapidly associated with depression, anxiety and irritability with the of version.

Not immediately hooked. Some people may take the same amount over a long period and not become dependent. The availability, lifestyle and personality are all factors. However, how can a cigarette from time to time, sometimes “-benign” use of recreational cocaine in normal light, sliding nasty long-term abuse.
In the worst cases can kill the cocaine psychosis – a condition not very nice to anxiety, insomnia, paranoia, anxiety, mood swings, lack of sexual appetite and weight loss.

Some organizations, existing drugs fight against cocaine psychosis as the inevitable consequence of occasional use. It is not. It should work, but it is easy to see how much you get.
Profile care centers, centers of local treatment are now learning more
but here is some good news: stop the coke, if you can, and will become normal.