Amphetamines stimulate dopamine production in the cells, cocaine blocks an enzyme called DAT whose normal function is to absorb dopamine neurons that discharge being the consequence of this blockage, a general increase of dopamine in the brain.
heroin binds to the neurotransmitter receptor and directly stimulates Refugio channels, nicotine and alcohol trigger a complex “chemical cascade which raises dopamine levels and there is also an unknown chemical in cigarettes that increases dopamine levels by blocking the enzyme MAO B. (more…)
